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A cyclodextrin-capped histone deacetylase inhibitor

✍ Scribed by Amin, Jahangir; Puglisi, Antonino; Clarke, James; Milton, John; Wang, Minghua; Paranal, Ronald M.; Bradner, James E.; Spencer, John

Book ID
120928799
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
476 KB
Volume
23
Category
Article
ISSN
0960-894X

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## Abstract Histone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients. The HDAC inh