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Histone deacetylase as a new target for cancer chemotherapy

✍ Scribed by Minoru Yoshida; Ryohei Furumai; Makoto Nishiyama; Yasuhiko Komatsu; Norikazu Nishino; Sueharu Horinouchi

Publisher
Springer
Year
2001
Tongue
English
Weight
192 KB
Volume
48
Category
Article
ISSN
0344-5704

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio