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Histone acetylation and chromatin signature in stem cell identity and cancer

✍ Scribed by Vivek Shukla; Thomas Vaissière; Zdenko Herceg

Book ID
113809095
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
596 KB
Volume
637
Category
Article
ISSN
0027-5107

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'The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.