Histone acetylation in chromatin and chromosomes
β Scribed by Bryan M. Turner; Laura P. O'Neill
- Book ID
- 112265183
- Publisher
- Elsevier Science
- Year
- 1995
- Weight
- 858 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1043-4682
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π SIMILAR VOLUMES
'The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.
The effect of histone acetylation was monitored on CHO chromatin structure, following the addition of 7 mM Na-butyrate to the cell culture medium. The properties of both control and hyperacetylated chromatins and nuclei were investigated by circular dichroism, ethidium bromide intercalation, differe