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Histone acetylation in chromatin structure and transcription

โœ Scribed by Grunstein, Michael


Book ID
109799503
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
262 KB
Volume
389
Category
Article
ISSN
0028-0836

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โœฆ Synopsis


'The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.


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Effects of histone acetylation on chroma
โœ Paola Gavazzo; Laura Vergani; Gian Carlo Mascetti; Claudio Nicolini ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 106 KB

The effect of histone acetylation was monitored on CHO chromatin structure, following the addition of 7 mM Na-butyrate to the cell culture medium. The properties of both control and hyperacetylated chromatins and nuclei were investigated by circular dichroism, ethidium bromide intercalation, differe