Highly Stereoselective Route toward the Synthesis of β- and γ-Amino Alcohols from Homochiral α- and β-Amino Acylsilanes as Synthetic Equivalents of α- and β-Amino Aldehydes
✍ Scribed by Bonini, Bianca F.; Comes-Franchini, Mauro; Mazzanti, Germana; Ricci, Alfredo; Sala, Massimiliano
- Book ID
- 125902748
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 112 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
aminoacylsilanes 1 and 13 and of the N-Ts-aminoacylsilane 5 with allyltrimethylsilane. Lower de values were obtained A practical route is described for the synthesis of enantiopure β-and γ-amino alcohols with two stereocenters, starting from in the Sc(OTf) 3 -catalyzed allylation of 5 with tetraally
Synthesis of Enantiopure β-and γ-Amino Alcohols from Homochiral α-and β-Aminoacylsilanes as Stable Synthetic Equivalents of α-and β-Amino Aldehydes. -The stereoselectivity is strongly dependent on both the type of protecting group and reagents used. -(BONINI, BIANCA