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Highly Enantioselective Hetero-Diels—Alder Reaction of Brassard Diene with Aromatic Aldehydes.

✍ Scribed by Qian Fan; Lili Lin; Jie Liu; Yaozong Huang; Xiaoming Feng; Guolin Zhang


Publisher
John Wiley and Sons
Year
2004
Weight
24 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract A new type of dendritic 2‐amino‐2′‐hydroxy‐1,1′‐binaphthyl (NOBIN)‐derived Schiff‐base ligands have been synthesized and applied to the titanium‐catalyzed hetero‐Diels–Alder reaction of Danishefsky's diene with aldehydes. These reactions afforded the corresponding 2‐substituted 2,3‐dihy