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Highly Diastereoselective One-Pot Synthesis of Spiro{cyclopenta[ a ]indene-2,2‘-indene}diones from 1-Indanones and Aromatic Aldehydes

✍ Scribed by Camps, Pelayo; Domingo, Luis R.; Formosa, Xavier; Galdeano, Carles; González, Diana; Muñoz-Torrero, Diego; Segalés, Sílvia; Font-Bardia, Mercè; Solans, Xavier


Book ID
126836435
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
211 KB
Volume
71
Category
Article
ISSN
0022-3263

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## Abstract Reaction of an isocyanide with an electron‐poor aromatic aldehyde in the presence of silica nanoparticles (silica NP; __ca.__ 42 nm) proceeds smoothly at room temperature to afford 2‐hydroxyacetamide derivatives in high yields (__Scheme 1__ and __Table 1__).