Highly Diastereoselective Domino Synthesis of 6-Spirosubstituted Pyrido[2,3- d ]pyrimidine Derivatives in Water
✍ Scribed by Jiang, Bo; Cao, Long-Ji; Tu, Shu-Jiang; Zheng, Wen-Rui; Yu, Hai-Zhu
- Book ID
- 117995561
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 154 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1520-4766
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## Abstract magnified image A series of 5,7‐diarylpyrido[2,3‐__d__]pyrimidine‐2,4(1__H__,3__H__)‐diones was synthesized __via__ the reaction of 6‐aminopyrimidine‐2,4‐dione and α,β‐unsaturated ketones in ionic liquid without using any catalyst. This protocol has the advantages of easier work‐up, mi
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