✦ LIBER ✦

A Simple Synthesis of Furo[3′,4′:5,6]pyrido[2,3-d]pyrimidine Derivatives through Multicomponent Reactions in Water

✍ Scribed by Shu-Jiang Tu; Yan Zhang; Hong Jiang; Bo Jiang; Jun-Yong Zhang; Run-Hong Jia; Feng Shi

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 133 KB
Volume: 2007
Category: Article
ISSN: 1434-193X
DOI: 10.1002/ejoc.200600913

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A series of furo[3′,4′:5,6]pyrido[2,3‐d]pyrimidine and indeno[2′,1′:5,6]pyrido[2,3‐d]pyrimidine derivatives were synthesized by three‐component reactions involving an aldehyde, 2,6‐diaminopyrimidine‐4(3__H__)‐one, and either tetronic acid or indane‐1,3‐dione in water, under microwave irradiation and traditional heating conditions, without use of any catalyst. This protocol has the advantages of higher yields, lower cost, reduced environmental impact, and convenience of procedure. The synthesis of a class of important compounds in aqueous medium has been achieved. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

📜 SIMILAR VOLUMES

A Simple Synthesis of Furo[3′,4′:5,6]pyr

A Simple Synthesis of Furo[3′,4′:5,6]pyrido[2,3-d]pyrimidine Derivatives Through Multicomponent Reactions in Water.

✍ Shu-Jiang Tu; Yan Zhang; Hong Jiang; Bo Jiang; Jun-Yong Zhang; Run-Hong Jia; Fen 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 25 KB

Synthesis and Anticonvulsant Activity of

Synthesis and Anticonvulsant Activity of Derivatives of Pyrano[4′,3′:4,5]pyrido[2,3-b]furo[3,2-d]pyrimidine and Pyrano[4′,3′:4,5]pyrido[2,3-b]furo[3,2-d]pyridine.

✍ E. G. Paronikyan; A. Kh. Oganisyan; A. S. Noravyan; R. G. Paronikyan; I. A. Dzha 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 131 KB 👁 1 views

ChemInform Abstract: Synthesis of Pyrido

ChemInform Abstract: Synthesis of Pyrido[2′,3′:4,5]thieno[2,3-d]pyrimidines Through Friedlaender Reactions.

✍ Shawkat A. Abdel-Mohsen; Ahmed A. Geies 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 42 KB 👁 1 views

Simple Analogues of Acyclonucleosides: S

Simple Analogues of Acyclonucleosides: Synthesis of N-Substituted Pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine Derivatives.

✍ Ahmed F. Khattab; Magdy A. Zahran; Ahmed Saif 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

A Convenient Synthesis of Novel Derivati

A Convenient Synthesis of Novel Derivatives of Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5,6-dione.

✍ Mosselhi A. N. Mosselhi 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 123 KB 👁 1 views

Synthesis and Structure of 2-Substituted

Synthesis and Structure of 2-Substituted Thieno[3′,2′:5,6]pyrido[4,3-d]pyrimidin-4(3H)-one Derivatives

✍ Jian-Chao Liu; Hong-Wu He; Ming-Wu Ding 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 96 KB 👁 1 views

## Abstract A series of new 2‐substituted 3‐(4‐chlorophenyl)‐5,8,9‐trimethylthieno[3′,2′: 5,6]pyrido[4,3‐__d__]pyrimidin‐4(3__H__)‐ones **8** were synthesized __via__ an aza‐__Wittig__ reaction. Phosphoranylideneamino derivatives **6a** or **6b** reacted with 4‐chlorophenyl isocyanate to give carbo