Many different materials have been suggested as solid supports for combinatorial chemistry, but cotton threads have only occasionally been used. Using a one-dimensional support necessitates clever methods for the generation of a library, and a recent publication describes an ingenious method for bot
Highlights from other journals - January 2001
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 33 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1464-3383
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โฆ Synopsis
Estrogen receptor ligands
Novel estrogens having tissue selective action suitable for menopausal hormone replacement or the treatment and prevention of breast cancer are current targets of interest. A solid phase parallel approach has been used to discover small molecule estrogen receptor ligands (Solidphase synthesis of tetrasubstituted pyrazoles, novel ligands for the estrogen receptor, S. R.
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