High yield acyl anion transfer reactions: nucleophilic acylation of aldehydes
β Scribed by Dietmar Seyferth; Robert M. Weinstein; Wei-Liang Wang; Richard C. Hui
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 199 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The acyl transfer reaction of __S__βglutathionyl benzoate (GSB) is catalyzed by a rationally designed mutant of human glutathione transferase A1β1, A216H. The catalyzed reaction proceeds via the formation of an acyl intermediate and has been studied in the presence of nitrogen, oxygen,
Nucleophile specificity of subtilisin (subtilopeptidase A) was studied via acyl transfer reactions in acetonitrile containing piperidine and 10 vol% of water. Ac-Tyr-OEt was used as acyl donor and a series of amino acid derivatives, diand tripeptides of the general structure Xaa-Gly, Gly-Xaa, Gly-Gl