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High specific activity 15-p-[123I]iodophenyl)pentadecanoic acid

✍ Scribed by Munawwar Sajjad; H.-J. Machulla; R.M. Lambrecht; Soliman Bakr

Book ID
103922281
Publisher
Elsevier Science
Year
1989
Weight
178 KB
Volume
40
Category
Article
ISSN
0883-2889

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✦ Synopsis

An improved labeling procedure for 15-(p-[123I]iodophenyl)pentadecanoic acid (IPPA) is reported. The exchange labeling yield was greater than 95%. The radiochemical yield is influenced by the presence of sodium. The major advantage of this method is that very high specific activity i.e. upto 190 mCi/mg labeled IPPA can be prepared.

πŸ“œ SIMILAR VOLUMES

Metabolism of 15 (p123I iodophenyl-)pent
Metabolism of 15 (p123I iodophenyl-)pentadecanoic acid in heart muscle and noncardiac tissues
✍ Sven N. Reske; Wolfgang Sauer; Hans-JΓΌrgen Machulla; Jochen Knust; Cuno Winkler πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 724 KB

The uptake and turnover of omega(p 123I iodophenyl-)pentadecanoic acid (I-PPA), a radioiodinated free-fatty-acid analog, was examined in the heart, lung, liver, kidneys, spleen, and skeletal muscle of rats. At 2 min post injection, a high cardiac uptake of 4.4% dose per gram had already been achieve