High risk factors for valvular heart disease from dopamine agonists in patients with Parkinson’s disease
✍ Scribed by Tomoko Oeda; Motoko Masaki; Kenji Yamamoto; Eiji Mizuta; Naoyuki Kitagawa; Tsuyoshi Isono; Satoshi Taniguchi; Kiyoshi Doi; Hitoshi Yaku; Chikao Yutani; Takashi Kawamura; Sadako Kuno; Hideyuki Sawada
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 245 KB
- Volume
- 116
- Category
- Article
- ISSN
- 1435-1463
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Valvular heart disease, associated with ergot derivative dopamine agonists, has been reported in patients with Parkinson's disease (PD). There are few comparative studies on the frequency, severity, and dose dependency of valvular disease associated with ergot derivatives. We analyzed these factors
## Abstract Fibrotic valvular heart disease (VHD) has been reported in association with ergot dopamine agonists (DAs), but the current database is insufficient regarding clinical relevance and comparison to data on non‐ergot DAs. We evaluated the effects of four DAs (pergolide, cabergoline, ropinir
## Abstract ## Objectives: Several observational studies suggest an association between treatment with ergoline‐derived dopamine agonists and valvular regurgitation. In this article, we present an overview of the literature and conduct a meta‐analysis. ## Methods: Observational studies addressin