✦ LIBER ✦

Valvular heart disease in Parkinson's disease treated with ergot derivative dopamine agonists

✍ Scribed by Ji-Youn Kim; Eun Joo Chung; Seung Woo Park; Won Yong Lee

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 105 KB
Volume: 21
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.20931

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✦ Synopsis

Valvular heart disease, associated with ergot derivative dopamine agonists, has been reported in patients with Parkinson's disease (PD). There are few comparative studies on the frequency, severity, and dose dependency of valvular disease associated with ergot derivatives. We analyzed these factors in 58 PD patients who were taking ergot derivatives (22 were taking bromocriptine and 36 were taking pergolide) and compared them with 20 age-matched controls based on the two-dimensional echocardiographic findings. Aortic, mitral, and tricuspid valvular thicknesses, as well as tenting areas and tenting distance of the mitral valve were measured. We also assessed the correlation be-

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