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High resolution methylation analysis of the galectin-1 gene promoter region in expressing and nonexpressing tissues

✍ Scribed by Paola Salvatore; Giovanna Benvenuto; Milena Caporaso; Carmelo B Bruni; Lorenzo Chiariotti


Book ID
117108625
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
352 KB
Volume
421
Category
Article
ISSN
0014-5793

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## Abstract ## BACKGROUND Microsatellite instability (MSI) has been reported in endometrial carcinoma (EC) and in colorectal carcinoma (CRC), primarily as a result of defective DNA mismatch repair (MMR). The MMR gene __hMLH1__ commonly is inactivated in both EC and CRC. In the current study, epige