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Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissues

โœ Scribed by Siane Lopes Bittencourt Rosas; Otavia Luisa Caballero; Seung Myung Dong; Maria da Gloria da Costa Carvalho; David Sidransky; Jin Jen

Book ID
117466887
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
212 KB
Volume
170
Category
Article
ISSN
0304-3835

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โœ Yutaka Tokumaru; Keishi Yamashita; Myoung Sook Kim; Hannah L. Park; Motonobu Osa ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 386 KB ๐Ÿ‘ 2 views

## Abstract PGP9.5 is a controversial molecule from an oncologic point of view. We recently identified frequent methylation of PGP9.5 gene exclusively in primary head and neck squamous cell carcinoma (HNSCC), suggesting that it could be a tumor suppressor gene. On the other hand, PGP9.5 was reporte