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High-Resolution Liquid Chromatography of Oligonucleotides on Nonporous Alkylated Styrene-Divinylbenzene Copolymers

✍ Scribed by C.G. Huber; P.J. Oefner; G.K. Bonn


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
630 KB
Volume
212
Category
Article
ISSN
0003-2697

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Keto and enol tautomers of chlortetracycline and 4-epichlortetracycline were successfully separated by low temperature high-performance liquid chromatography on poly(styrene-divinylbenzene)copolymer. The keto-enol tautomerism occurs between C-11a and C-12. The elucidation of the chemical structure o