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High-resolution in vivo measurements of transverse relaxation times in rats at 7 Tesla

✍ Scribed by Yannick Crémillieux; Shujun Ding; Jeff F. Dunn

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
652 KB
Volume
39
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

A multi‐echo imaging sequence suitable for high‐resolution and accurate in vivo transverse relaxation time (T~2~) mapping has been implemented. The sequence was tested on phantoms and was used to measure T~2~ values in vivo in the rat brain, muscle, and fat at 7 T. Brain T~2~ maps are shown and regional variations in brain T~2~ are reported (41.8 ms in cortex, 47.9 ms in hippocampus). Results are compared to literature values obtained at lower field in vivo as well as high‐field T~2~ measurements on excised rat tissues. The reported T~2~ values are generally smaller compared to lower‐field‐strength literature values. A discussion of the possible causes of these field effects on T~2~ is included (dipolar interaction, fast chemical exchange, and diffusion in susceptibility gradients).

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