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High-resolution DNA melting curve analysis to establish HLA genotypic identity

✍ Scribed by L. Zhou; J. Vandersteen; L. Wang; T. Fuller; M. Taylor; B. Palais; C.T. Wittwer


Book ID
110891999
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
289 KB
Volume
64
Category
Article
ISSN
0001-2815

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High Resolution Melting Analysis (HRMA) is a rapid and sensitive method for single nucleotide polymorphism (SNP) analysis. In the present study we present a novel HRMA assay to detect three SNPs in close proximity of each other in the first exon of the gene encoding mannose-binding lectin (MBL), a k