## Abstract The separation of 12 model compounds chosen among purine and pyrimidine bases and nucleosides was studied by using hydrophilic interaction chromatography (HILIC). The compounds investigated were small molecules with relevant properties for biomedical and pharmaceutical studies. The mixt
High-pressure liquid chromatography: I. Quantitative separation of purine and pyrimidine nucleosides and bases
β Scribed by Youcef M. Rustum
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 547 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0003-2697
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In the course of determining 6-mercaptopurine (6MP) metabolites formed in 6MP-treated cultured cells or in animal tissues, on the base and (deoxy-)ribonucleoside levels a method has been established for the separation and quantitative determination of picomole amounts of 15 purine and Gthiopurine co
Nucleotides, nucleosides, and purine bases were extracted from human endomyocardial biopsies, freeze-clamped rat hearts, and porcine coronary sinus plasma. Perchloric acid extracts were neutralized with Freon-trioctylamine and analyzed at 250 nm by reverse-phase ion-pairing high-performance liquid c