𝔖 Bobbio Scriptorium
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High-performance Liquid Chromatography/NMR Spectrometry/Mass Spectrometry:Further Advances in Hyphenated Technology

✍ Scribed by Holt, R. M.; Newman, M. J.; Pullen, F. S.; Richards, D. S.; Swanson, A. G.

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
395 KB
Volume
32
Category
Article
ISSN
1076-5174

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✦ Synopsis

The earlier use of combined liquid chromatography/NMR spectrometry/mass spectrometry (LC/NMR/MS) involved the use of a particle beam interface. This paper describes further developments of this hyphenated technology, in particular the incorporation of an electrospray interface into the LC/NMR/MS system. This improved LC/NMR/MS system was designed for the support of a combinatorial library program. The power of this technique is demonstrated in the successful structural elucidation of each compound in a mixture of commercially available peptides.

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