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High-performance liquid chromatographic purification of endogenous tumour cell growth inhibitory peptides

✍ Scribed by Niels M. Barfod

Book ID
108447813
Publisher
Elsevier Science
Year
1982
Weight
453 KB
Volume
230
Category
Article
ISSN
0378-4347

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High-performance liquid chromatographic purification of peptide hormones: Ovine hypothalamic amunine (corticotropin releasing factor)
✍ J. Rivier; C. Rivier; J. Spiess; W. Vale πŸ“‚ Article πŸ“… 1982 πŸ› Elsevier Science 🌐 English βš– 590 KB

Amunine, or corticotropin releasing factor (CRF), a 41-peptide amide, has been isolated from ovine hypothalami. Tissues were extracted, defatted, and partitioned prior to being sized by gel permeation. The active zone followed by a sensitive in vitro assay (CRF-mediated corticotropin release from pi