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High-performance liquid chromatographic method for the determination of diprophylline in human serum

✍ Scribed by N. Paterson

Book ID
108449759
Publisher
Elsevier Science
Year
1982
Weight
439 KB
Volume
232
Category
Article
ISSN
0378-4347

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High performance liquid chromatographic
High performance liquid chromatographic method for determination of canrenone in serum
✍ Besenfelder, E. ;Endele, R. πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 215 KB πŸ‘ 2 views

Spironolactone (I), a potassium sparing diuretic, is widely used in the treatment of edema. Metabolic degradation starts with rapid deacetylation, leading to the short lived a-thiol [l]. Subsequent elimination of hydrogen sulfide yields canrenone (II), which exists in enzymatic equilibrium with canr