Spironolactone (I), a potassium sparing diuretic, is widely used in the treatment of edema. Metabolic degradation starts with rapid deacetylation, leading to the short lived a-thiol [l]. Subsequent elimination of hydrogen sulfide yields canrenone (II), which exists in enzymatic equilibrium with canr
High-performance liquid chromatographic method for the determination of dextropropoxyphene and nordextropropoxyphene in serum
✍ Scribed by Helle Riis Angelo; Torben Kranz; Jens Strøm; Birgit Thisted; Mogens Bredgaard Sørensen
- Publisher
- Elsevier Science
- Year
- 1985
- Weight
- 389 KB
- Volume
- 345
- Category
- Article
- ISSN
- 0378-4347
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