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High-performance liquid chromatographic method for the assay of TA-3090 and its pharmacokinetic parameters in healthy volunteers

✍ Scribed by Marc Lefebvre; D. Garceau; J. Spenard; J.M. Houle; D. Major; G. Caille


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
366 KB
Volume
7
Category
Article
ISSN
0731-7085

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A high-performance liquid chromatographi
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A high-performance liquid chromatographic method was developed to determine stobadin pharmacokinetics in dog and man. The relative bioavailability of stobadin dipalmitate compared with dihydrochloride was 46.4 per cent in dog. In man peak serum concentrations ranged from 12 to 289 ng ml-1 after a si