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High-performance liquid chromatographic determination of creatinine in serum, and a correlation of the results with those of the Jaffé and enzymic methods

✍ Scribed by P. Schneiderka; V. Pacáková; K. Štulík; M. Kloudová; K. Jelínková

Publisher
Elsevier Science
Year
1993
Weight
480 KB
Volume
614
Category
Article
ISSN
0378-4347

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A high-performance liquid chromatographic method was developed to determine stobadin pharmacokinetics in dog and man. The relative bioavailability of stobadin dipalmitate compared with dihydrochloride was 46.4 per cent in dog. In man peak serum concentrations ranged from 12 to 289 ng ml-1 after a si