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High-performance liquid chromatographic assay of 6-methylthioguanine, a major metabolite of 6-thioguanine, in urine

โœ Scribed by Trevor Dooley; John L. Maddocks


Publisher
Elsevier Science
Year
1985
Weight
424 KB
Volume
337
Category
Article
ISSN
0378-4347

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โœ Lawrence E. Lavi; John S. Holcenberg ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 635 KB

A highly sensitive and rapid assay for the detection of 6-mercaptopurine metabolites in the red blood cells-of leukemic patients receiving the drug has been developed. The method employs a batchchromatographic procedure using a mercurial cellulose resin to selectively absorb thiol compounds combined