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High-frequency stimulation of the subthalamic nucleus silences subthalamic neurons: a possible cellular mechanism in Parkinson’s disease

✍ Scribed by C Magariños-Ascone; J.H Pazo; O Macadar; W Buño

Book ID
117490775
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
268 KB
Volume
115
Category
Article
ISSN
0306-4522

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High-frequency stimulation of the subthalamic nucleus (STN) is a promising therapeutic approach in patients with severely disabling Parkinson's disease (PD). Whereas STN stimulation improves the cardinal signs of PD, little is known about the effects of STN stimulation on fine manual skills like han