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High Frequency of TP53 Mutations in Juvenile Pilocytic Astrocytomas Indicates Role of TP53 in the Development of These Tumors

✍ Scribed by Vanessa M. Hayes; Clemens M.F. Dirven; Anke Dam; Edwin Verlind; Willemina M. Molenaar; Jan Jakob A. Mooij; Robert M.W. Hofstra; Charles H.C.M. Buys

Book ID
111403948
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
84 KB
Volume
9
Category
Article
ISSN
1015-6305

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## Abstract In an attempt to correlate the __TP53__ mutation pattern of squamous cell carcinomas of the esophagus (ESCC) and life style factors of patients from the high risk area Rio Grande do Sul, Brazil, 135 ESCC were analyzed, after prescreening by p53 immunohistochemistry, by SSCP and DNA sequ