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Number of somatic mutations in the mitochondrial D-loop region indicates poor prognosis in breast cancer, independent of TP53 mutation

โœ Scribed by Shou-Jen Kuo; Ming Chen; Gwo-Chin Ma; Shou-Tung Chen; Shun-Ping Chang; Wen-Yin Lin; Yen-Chieh Chen; Tsung-Hsien Lee; Ta-Tsung Lin; Chin-San Liu

Book ID
113513781
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
163 KB
Volume
201
Category
Article
ISSN
0165-4608

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TP53 in gastric cancer: Mutations in the
TP53 in gastric cancer: Mutations in the L3 loop and LSH motif DNA-binding domains of TP53 predict poor outcome
โœ Manuela Migliavacca; Laura Ottini; Viviana Bazan; Valentina Agnese; Simona Corsa ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB

## Abstract The aim of this study was to clarify whether specific p53 mutations may have biological relevance in terms of disease relapse or death in gastric carcinomas (GC). Resected specimens from a consecutive series of 62 patients with GC undergoing potentially curative surgery were prospective