𝔖 Bobbio Scriptorium
✦   LIBER   ✦

High frequency of Parkin exon rearrangements in Mexican-mestizo patients with early-onset Parkinson's disease

✍ Scribed by Jorge Luis Guerrero Camacho; Nancy Monroy Jaramillo; Petra Yescas Gómez; Mayela Rodríguez Violante; Catherine Boll Woehrlen; Ma. Elisa Alonso Vilatela; Marisol López López


Book ID
112143424
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
565 KB
Volume
27
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Novel parkin mutations detected in patie
✍ Aida M. Bertoli-Avella; José L. Giroud-Benitez; Ali Akyol; Egberto Barbosa; Onno 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 141 KB

## Abstract A multiethnic series of patients with early‐onset Parkinson's disease (EOP) was studied to assess the frequency and nature of __parkin__/PARK2 gene mutations and to investigate phenotype–genotype relationships. Forty‐six EOP probands with an onset age of <45 years, and 14 affected relat

Analysis of PARK2 gene exon rearrangemen
✍ Elena V. Semenova; Maria I. Shadrina; Pyotr A. Slominsky; Irina A. Ivanova-Smole 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 1006 KB

## Abstract ## Background: Deletions and duplications of single exons or exon groups account for a large proportion of the __PARK2__ gene mutations described in juvenile autosomal recessive Parkinson's disease (PD). ## Methods: We analyzed rearrangements in exons 1 to 12 of the __PARK2__ gene in

Detection of Parkin (PARK2) and DJ1 (PAR
✍ Ana Djarmati; Katja Hedrich; Marina Svetel; Nora Schäfer; Vladislava Juric; Slob 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 59 KB 👁 1 views

## Mutations in the Parkin (PARK2) and the DJ1 (PARK7) gene cause early-onset Parkinson disease (EOPD). We tested 75 Serbian EOPD patients for mutations in both genes by conventional mutational screening (SSCP/dHPLC/sequencing) to detect small sequence alterations and by gene dosage studies (quanti