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High frequency of EBV association and 30-bp deletion in the LMP-1 gene in CD56+ lymphomas of the upper aerodigestive tract

✍ Scribed by Yan-Chin Tai; Lian-Hua Kim; Suat-Cheng Peh


Book ID
115175269
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
544 KB
Volume
54
Category
Article
ISSN
1320-5463

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A specific variant of Epstein-Barr virus (EBV) with a 30-bp deletion in the C-terminal region of the LMP1 gene has been found in some EBV-associated malignancies. To better understand the tumorigenic role of this LMP1 variant, we used PCR and sequencing to examine the LMP1 gene in 38 EBVassociated c