Background and aim: EBV is an important virus in the pathogenesis of NHL. VEGF-A is the essential factor in tumor angiogenesis. There is evidence of cross talk between angiogenesis and viral carcinogenesis. The viral latent protein LMP1, may play a role by inducing expression of angiogenic factors I
โฆ LIBER โฆ
Mutual regulation of EBV LMP1 and CD99 in the pathogenesis of EBV-associated Hodgkin lymphomas
โ Scribed by Hye Sook Min; Im-Soon Lee; Seong Hoe Park
- Book ID
- 118078354
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2008
- Tongue
- English
- Weight
- 552 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1755-9294
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A radioimmunoassay (RIA) has been developed and used to determine the expression of LMP-a membrane protein encoded by the LT3 region of the Epstein-Barr virus (EBV) genome-in cell lines of various origins. The RIA was highly sensitive, specific and reproducible. All EBV-negative cell lines were LMP-