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High expression of p300 in human breast cancer correlates with tumor recurrence and predicts adverse prognosis

✍ Scribed by Xiang-sheng Xiao; Mu-yan Cai; Jie-wei Chen; Xin-yuan Guan; Hsiang-fu Kung; Yi-xin Zeng; Dan Xie

Book ID
107467082
Publisher
Chinese Anti-Cancer Association
Year
2011
Tongue
English
Weight
667 KB
Volume
23
Category
Article
ISSN
1000-9604

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TIMP-2 is an endogenous inhibitor of MMPs. Most data from model systems suggest that high levels of this inhibitor prevent metastasis. In human breast cancers, however, we show that high levels of TIMP-2 correlate with both shortened disease-free interval and overall survival. In primary breast canc