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High Enantioselectivity in Rhodium-Catalyzed Allylic Alkylation of 1-Substituted 2-Propenyl Acetates

โœ Scribed by Hayashi, Tamio; Okada, Atsushi; Suzuka, Toshimasa; Kawatsura, Motoi


Book ID
127357907
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
72 KB
Volume
5
Category
Article
ISSN
1523-7060

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The palladium catalyzed allylic alkylati
โœ Donna L. Romero; Edward L. Fritzen ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 199 KB

Palladium catalyzed asymmetric allylic alkylations of a bis(trimethylsilyl) substituted propenyl acetate and carbonate were investigated using various chiral ligands and reaction conditions. The best enantioselectivity (86% e.e.) was obtained with the substrate l-phenyl-3,3-bis(trimethylsilyl)propen