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High-dose ifosfamide by infusion with mesna in advanced soft tissue sarcoma

✍ Scribed by Stuart-Harris, R.; Harper, P.G.; Kaye, S.B.; Wiltshaw, E.

Book ID
122543011
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
116 KB
Volume
10
Category
Article
ISSN
0305-7372

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High-dose alkylation therapy using ifosfamide infusion with mesna in the treatment of adult advanced soft-tissue sarcoma
✍ Robin C. Stuart-Harris; Peter G. Harper; Colin A. Parsons; Stanley B. Kaye; Caro πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 463 KB

In a phase II study, 42 patients with advanced soft-tissue sarcoma were treated with ifosfamide by 24-h infusion and mesna by 4-h IV bolus, repeated every 3 weeks. Ten patients received ifosfamide 5.0 g/m2, 20 had the dosage increased to 8.0 g/m2, and 12 received 8.0 g/m2 from the outset. Mesna was