Treatment of advanced, high-grade soft-tissue sarcoma with ifosfamide and continuous-infusion etoposide
✍ Scribed by Gunnar Sæter, Kristian Talle, Øyvin P. Solheim
- Book ID
- 120776442
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 357 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0344-5704
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In a phase II study, 42 patients with advanced soft-tissue sarcoma were treated with ifosfamide by 24-h infusion and mesna by 4-h IV bolus, repeated every 3 weeks. Ten patients received ifosfamide 5.0 g/m2, 20 had the dosage increased to 8.0 g/m2, and 12 received 8.0 g/m2 from the outset. Mesna was
Our objective was to assess the efficacy of a standard dose ifosfamide and doxorubicin containing regimen in the treatment of advanced soft tissue sarcomas. Forty consecutive patients with a median age of 35.5 years were treated. Ifosfamide was administered at a dose of 2.5 g/m 2 /day as 72-hour con