Ifosfamide plus mesna with and without adriamycin in soft tissue sarcoma
β Scribed by E. Wiltshaw; G. Westbury; C. Harmer; A. McKinna; C. Fisher
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 263 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0344-5704
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π SIMILAR VOLUMES
In a phase II study, 16 adult patients with locally advanced or metastatic soft tissue sarcomas were treated with i.v. infusions of ifosfamide/mesna 5 g/m2 plus i.v. doxorubicin 40 mg/m2. Courses were given every 3 weeks up to a maximum of six courses in responding patients. Six patients (37.5%) had
In a phase II study, 42 patients with advanced soft-tissue sarcoma were treated with ifosfamide by 24-h infusion and mesna by 4-h IV bolus, repeated every 3 weeks. Ten patients received ifosfamide 5.0 g/m2, 20 had the dosage increased to 8.0 g/m2, and 12 received 8.0 g/m2 from the outset. Mesna was