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High-dose cytosine arabinoside therapy in acute non-lymphocytic leukemia

โœ Scribed by Preisler, Harvey D.


Book ID
123256480
Publisher
Elsevier Science
Year
1984
Weight
461 KB
Volume
20
Category
Article
ISSN
0277-5379

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High-dose cytosine arabinoside: Clinical
โœ Early, A. P. ;Preisler, H. D. ;Higby, D. J. ;Brecher, M. ;Browman, G. ;McBride, ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 664 KB

High dose cytosine arabinoside (HD-AraC) was evaluated 1) as remission induction therapy for refractory acute leukemia and high risk AML, 2) as augmentation therapy for acute leukemia, and 3) as conditioning therapy prior to allogeneic bone marrow transplantation for acute leukemia. Seven of 10 pati

High dose cytosine arabinoside (HDARAC)
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Thirteen leukemic patients with disease refractory to conventional chemotherapy were treated with 1.0 to 7.5 g/m2 of Cytosine Arabinoside (Ara-C) over 29 drug cycles. Drug infusions were spaced at 12-hour intervals; a maximum of four doses was administered over 36 hours. After single dose tolerance