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High density fed-batch cultures for hybridoma cells performed with the aid of a kinetic model

✍ Scribed by R. Pörtner; A. Schilling; I. Lüdemann; H. Märkl

Publisher
Springer
Year
1996
Tongue
English
Weight
839 KB
Volume
15
Category
Article
ISSN
1615-7605

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✦ Synopsis

Hybridoma fed-batch cultures with either standard medium as feed or concentrated medium as feed and removal of toxic metabolites through dialysis were performed by using model calculations for "a priori" determination of process parameters. In a first step a kinetic model for specific growth

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