A fed-batch cell culture process was developed that has general applicability to all evaluated Sp2/0 (n = 8) and NS0 (n = 1) antibody-producing cell lines. The two key elements of this generic process were a protein-free concentrated feed medium, and a robust, metabolically responsive feeding strate
Multiple-model control strategy for a fed-batch high cell-density culture processing
β Scribed by Yu-Cheng Chung; I-Lung Chien; Der-Ming Chang
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 873 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0959-1524
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