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Heuristic Optimization of Antibody Production by Chinese Hamster Ovary Cells

โœ Scribed by Sandeepa Sandadi; Semsi Ensari; Brian Kearns

Book ID
109387274
Publisher
American Institute of Chemical Engineers
Year
2005
Tongue
English
Weight
150 KB
Volume
21
Category
Article
ISSN
8756-7938

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## Abstract In this study, we systematically compare two vector design strategies for recombinant monoclonal antibody (Mab) synthesis by Chinese hamster ovary (CHO) cells; a dual open reading frame (ORF) expression vector utilizing separate cytomegalovirus (CMV) promoters to drive heavy chain (HC)