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Heterologous production of epothilones B and D inStreptomyces venezuelae

✍ Scribed by Sung Ryeol Park; Je Won Park; Won Seok Jung; Ah Reum Han; Yeon-Hee Ban; Eun Ji Kim; Jae Kyung Sohng; Sang Jun Sim; Yeo Joon Yoon

Publisher
Springer
Year
2008
Tongue
English
Weight
257 KB
Volume
81
Category
Article
ISSN
1432-0614

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Optimizing the heterologous production of epothilone D in Myxococcus xanthus
✍ Janice Lau; Scott Frykman; Rika Regentin; Sally Ou; Hiroko Tsuruta; Peter Licari πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 219 KB πŸ‘ 2 views

## Abstract The heterologous production of epothilone D in __Myxococcus xanthus__ was improved by 140‐fold from an initial titer of 0.16 mg/L with the incorporation of an adsorber resin, the identification of a suitable carbon source, and the implementation of a fed‐batch process. To reduce the deg