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ChemInform Abstract: The Epothilones: Biosynthesis and Heterologous Production of Epothilones

✍ Scribed by Rolf Mueller

Publisher
John Wiley and Sons
Year
2009
Weight
15 KB
Volume
40
Category
Article
ISSN
0931-7597

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## Abstract The heterologous production of epothilone D in __Myxococcus xanthus__ was improved by 140‐fold from an initial titer of 0.16 mg/L with the incorporation of an adsorber resin, the identification of a suitable carbon source, and the implementation of a fed‐batch process. To reduce the deg