Heterologous expression of membrane proteins in cardiac myocytes
โ Scribed by Miroslav Radenkovic; Halyna Pankevych; Oliver Kudlacek; Ingrid Gsandtner; Karlheinz Hilber
- Publisher
- BioMed Central
- Year
- 2007
- Tongue
- English
- Weight
- 79 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1471-2210
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๐ SIMILAR VOLUMES
Missense substitutions and processivity errors in the translation of heterologous proteins are expected to occur at higher frequencies than the corresponding errors of normal translation. The resulting error-containing products may overload chaperone systems. Likewise, there may be a risk of an immu
Stable transformed insect cell lines have been used for producing many highly processed heterologous proteins. Current research has focused on development of new expression and selection systems, and enhancement of vector stability. Defining the variation of modification and processing capabilities
To understand the role of tissue adaptation to altered physiological states, a more physiologically and dimensionally relevant in vitro model of cardiac myocyte organization has been developed. A microtextured polymeric membrane with micron range dimensions promotes myocyte adhesion through substrat
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The contractile cells in the heart (the cardiac myocytes) are terminally differentiated. In response to pathophysiological stresses, cardiac myocytes undergo hypertrophic growth or apoptosis, responses associated with the development of cardiac pathologies. There has been much effort ex