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Heterogeneous dopamine receptor changes in early and late Huntington's disease

✍ Scribed by Richfield, Eric K.; O'Brien, Christopher F.; Eskin, Thomas; Shoulson, Ira

Book ID
122965429
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
649 KB
Volume
132
Category
Article
ISSN
0304-3940

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## Abstract Huntington's disease (HD) is a neurodegenerative disorder, primarily affecting medium spiny neurones in the striatum. The density of striatal dopamine D~2~ receptors is reduced in HD but there is little known about this biomarker in brain regions outside the striatum. The primary object