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Changes in striatal dopamine D2 receptor binding in pre-clinical Huntington’s disease

✍ Scribed by J.C.H. Van Oostrom; M. Dekker; A.T.M. Willemsen; B.M. De Jong; R.A.C. Roos; K.L. Leenders


Book ID
111065732
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
134 KB
Volume
16
Category
Article
ISSN
1351-5101

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Extrastriatal dopamine D2 receptor bindi
✍ Mouna Esmaeilzadeh; Lars Farde; Per Karlsson; Andrea Varrone; Christer Halldin; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB

## Abstract Huntington's disease (HD) is a neurodegenerative disorder, primarily affecting medium spiny neurones in the striatum. The density of striatal dopamine D~2~ receptors is reduced in HD but there is little known about this biomarker in brain regions outside the striatum. The primary object