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Lack of GTP-insensitive D2 dopamine receptors in Huntington's disease

✍ Scribed by Jacques De Keyser; Raymund A.C. Roos; Guy Ebinger; Georges Vauquelin

Book ID
118930807
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
437 KB
Volume
92
Category
Article
ISSN
0022-510X

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## Abstract Huntington's disease (HD) is a neurodegenerative disorder, primarily affecting medium spiny neurones in the striatum. The density of striatal dopamine D~2~ receptors is reduced in HD but there is little known about this biomarker in brain regions outside the striatum. The primary object