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Heterogeneity ofp53Mutational Status in Intramucosal Carcinoma of the Colorectum

✍ Scribed by Yamada, Satoshi ;Ajioka, Yoichi ;Watanabe, Hidenobu ;Hashidate, Hideki ;Takaku, Hideya ;Kazama, Shinsuke ;Yokoyama, Junji ;Nishikura, Ken ;Fujiwara, Takato ;Asakura, Hitoshi

Book ID
108581989
Publisher
Wiley (Blackwell Publishing)
Year
2001
Tongue
English
Weight
976 KB
Volume
92
Category
Article
ISSN
0910-5050

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## Communicated by Albert de la Chapelle PTEN regulates cell homeostasis by inhibiting growth signals transduced through PI3kinases. The gene is mutated in several cancer types, but so far, only a limited number of mutations have been reported in colorectal cancer. In the present study, direct seq